4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo-[4,3-d]pyrimidin-5-yl)benzene-1-sulfo - Names and Identifiers
Name | 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
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Synonyms | Sildenafil Chlorosulfone IMpurity Sildenafil Chlorosulfonyl IMpurity 5-(5-CHLOROSULFONYL-2-ETHOXY PHENYL)-1-METHYL-3-N-PROPYL-1 3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1 H-pyrazolo-(4-3-d)-pyrimidine-5 4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo-[4,3-d]pyrimidin-5-yl)benzene-1-sulfo 5-(5-Chlorosulfonyl-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonyl chloride 3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxy-benzenesulfonyl Chloride 4-Ethoxy-3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyriMidin-5-yl)benzene-1-sulfonyl chloride
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CAS | 139756-22-2
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InChI | InChI=1/C17H19ClN4O4S/c1-4-6-12-14-15(22(3)21-12)17(23)20-16(19-14)11-9-10(27(18,24)25)7-8-13(11)26-5-2/h7-9H,4-6H2,1-3H3,(H,19,20,23) |
4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo-[4,3-d]pyrimidin-5-yl)benzene-1-sulfo - Physico-chemical Properties
Molecular Formula | C17H19ClN4O4S
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Molar Mass | 410.88 |
Density | 1.48±0.1 g/cm3(Predicted) |
Melting Point | 180-182°C |
Boling Point | 621.4°C at 760 mmHg |
Flash Point | 329.6°C |
Solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
Vapor Presure | 2.29E-15mmHg at 25°C |
Appearance | Solid |
Color | White to Pale Beige |
pKa | 9.87±0.20(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
Stability | Moisture Sensitive |
Refractive Index | 1.663 |
4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo-[4,3-d]pyrimidin-5-yl)benzene-1-sulfo - Introduction
1-Methyl -3-propyl -5-(2-ethoxy-5-chlorosulfonyl) phenyl -1, 6-dihydro-7H-pyrazolo [4,3-d] pyrimidin-7-one is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless crystalline solid
-Molecular formula: C19H20ClNO4S
-Molecular weight: 403.88g/mol
-Melting point: 110-115°C
-Boiling Point: 490.4°C at 760 mmHg
-Solubility: Soluble in organic solvents, such as dimethyl sulfoxide and ether
Use:
- 1-Methyl -3-propyl -5-(2-ethoxy-5-chlorosulfonyl) phenyl -1, 6-dihydro-7H-pyrazolo [4,3-d] pyrimidin-7-one is an important pharmaceutical intermediate, commonly used in the preparation of drugs and pesticides.
Preparation Method:
The synthesis method of -1-methyl -3-propyl -5-(2-ethoxy-5-chlorosulfonyl) phenyl -1, 6-dihydro-7H-pyrazolo [4,3-d] pyrimidin-7-one is more complicated, and generally requires multi-step reactions. The specific synthetic method may vary depending on the preparation objectives and laboratory conditions.
Safety Information:
- 1-Methyl -3-propyl -5-(2-ethoxy-5-chlorosulfonyl) phenyl -1, 6-dihydro-7H-pyrazolo [4,3-d] pyrimidine -7-One is an organic compound that may have some adverse effects on the human body. When handling this compound, it is necessary to take appropriate safety measures, such as wearing protective gloves and goggles, and ensuring a well-ventilated working environment. In addition, the relevant safety data sheets should be consulted for specific safety and protection information.
Last Update:2024-04-09 20:52:54